Analysis:

Test	Result	Legal specification
Identification	Positive	As compared with authentic sample by using IR and HPLC methods
M p °C	211-214	No specification
[a]D25(CH3OH)	-51.15°	No specification
Moisture	0.46%	No more than 2.5%
Impurity	1.01%	No more than 2.0% (by using HPLC method)
Assay	99.60%	No less than 98.0% (on anhydrous basis by using HPLC method)

Appearance:                Yellow-green powder
Paclitaxel Assay:         73.23%
Method of Analysis:     HPLC (Internal standard)     

Also known as 4’-Cyano-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-3’-(trifluoromethyl)-propionanilide

References:
1. J. Med. Chem. 1988, 31, 954-959.
2. J. Am. Chem. Soc. 1954, 76, 1051-1054.


For laboratory research use only; high affinity progesterone antagonist; Minimum purity: 98% (C₂₉H₃₅ NO₂)

Also known as ±)-5-[4-[(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]-benzyl]-2,4-thiazolidinedione

References:
1. J. Med. Chem. 1989, 32, 421-428.
2. J. Med. Chem. 1996, 39, 5053-5063.


PS is extracted from porcine lung. It is composed of 99% polar lipids and 1% apoproteins. The phospholipid component consists primarily of phosphatidylcholine and its derivatives. It is indicated in treatment of respiratory distress syndrome.


Defibrase is extracted from Agkistrodon actum venom. It is a serine proteinase and has defibrinogenation effects on peripheral circulation and on experimental glomerulonephritis. It is indicated as anticoagulant.
Description:   White lyophilized powder
Solution (5 BU/ml):   Clear and colorless
pH:   6.0
Potency:   > 2,000 BU/mg protein
Specific activity:   > 2,000 BU/mg protein
Molecular weight:   ~ 35,000
Purity (HPLC):   > 95%
Pyrogen:   Free at 4.0 BU/ml/kg rabbit
Hypersensitivity test:   Not detectable
Abnormal toxicity:   Absent at 1.0 BU/0.5ml/mouse
Bleeding toxicity:   Absent at 1.0 BU/0.2ml/mouse
Loss on drying:   < 2%


HCG is extracted from pregnant women’s urine. It is a glycoprotein hormone synthesized by chorionic tissue of the placenta to maintain the function of the corpus luteum and to stimulate ovarian steroid secretion in the early stages of gestation. It is now indicated for male hypogonadism secondary to pituitary failure, induction of ovulation and pregnancy in the anovulatory infertile woman, etc.

Appearance: White or cream white powder
Solubility (1% in water):   Complete and clear
Activity:   N.L.T. 3,500 IU/mg protein
Specific activity:   N.L.T. 5,000 IU/mg protein
pH:   5.5 - 7.0
Loss on drying:   N.M.T. 5%
Protease:   N.M.T. 3 UA/mg protein
Pyrogen:   Free at 1,500 IU/kg rabbit
Hepatitis A antibody:   Negative
Hepatitis B surface antigen:   Negative
Hepatitis B antigen "E":   Negative
Hepatitis C antibody:   Negative
HIV I antigen:   Negative 

HMG is extracted from menopause women’s urine and contains FSH and LH.
Form I:
Appearance:   White or slightly yellow powder
FSH Activity:   N.L.T. 100 IU/mg protein
LH Activity:   N.L.T. 25 IU/mg protein
FSH/LH:   5:1 - 3:1
pH:   6.0 - 7.5
Pyrogen:   Pass (5.0 IU/kg rabbit)
Loss on drying:   N.M.T. 5%
Hepatitis A antibody:   Negative
Hepatitis B antigen "E":  Negative
Hepatitis C antibody:   Negative
HIV antibody:   Negative
HIV I antigen:   Negative

Form II:
Appearance:   White or slightly yellow powder
FSH activity:   N.L.T. 80 IU/mg protein
LH Activity:   N.L.T. 80 IU/mg protein
FSH/LH:   1:1
pH:   6.0 - 7.5
Pyrogen:   Pass (5.0 IU/kg rabbit)|
Loss on drying:   N.M.T. 5%
Hepatitis A antibody:   Negative
Hepatitis B antigen "E":   Negative|
Hepatitis C antibody:   Negative
HIV antibody:   Negative
HIV I Antigen:   Negative  

UK is extracted from healthy men's urine. It is a serine protease, which activates plasminogen to plasmin. UK is indicated for acute myocardial infarction, venous thrombosis, etc.
Appearance:   White lyophilized powder
Identification:   Positive
Fibrinolytic activity:   N.L.T. 10,000 IU/mg protein
Specific activity:   N.L.T. 120,000 IU/mg Protein
High molecular weight UK:   > 95%
pH:   6.0 - 7.5
Sodium chloride:   < 400 mg/ml
Abnormal toxicity:   Absent at 100,000 IU/ml/kg mouse
HIV/HBsAg:   Negative
Pyrogen:   Free at 20,000 IU/kg rabbit



UTI is extracted from healthy men's urine. It is an acid-stable glycoprotein containing two Kunitz-type protease inhibitor domains and two carbohydrate side chains. UTI is a broad-spectrum enzyme inhibitor. Apart from the proteolytic activity, it also inhibits lipases, etc. UTI is being developed for the treatment of acute pancreatitis.

Appearance:   White or slight yellow powder
Activity:   N.L.T. 1,500 U/mg protein
Specific activity:   N.L.T. 2,500 U/mg protein
pH:   5.0 - 7.5
Kallikrein:   N.M.T. 0.05/50,000 U
High molecular weight UTI:   N.L.T. 90%
Endotoxin:   N.M.T. 100 EU/50,000 U
Loss on drying:   N.M.T. 5%


Interferon a-2b is produced using recombinant DNA technology. It is a highly homologous species-specific protein that inhibits viral replication and cell proliferation, and modulates the immune response. It also has antiviral and antineoplastic effects.

Appearance:   Colorless liquid
Molecular weight:   19,000
Purity (HPLC):   N.L.T. 95%
Purity (SDS-PAGE):   N.L.T. 95%
Specific activity:   N.L.T. 1 x 108 IU/mg protein
Pyrogen (5 x 106 IU/vial):   Pass
Sterility test:   Pass
Safety test:   Pass
Exogenous DNA (pg):   Pass
HBsAg:   Negative